Recently, Bota Bio (“Bota“ hereafter) announced the commercial introduction of Prorylia™ LF, a flagship personal care ingredient developed by its wholly owned subsidiary, Yucca Elements (“Yucca“ hereafter), which is now being used in a range of personal care products available on the market.
Prorylia™ LF is designed to support skin barrier stability and help modulate inflammatory responses. By effectively relieving redness and sensitivity, the ingredient responds to growing consumer demand for skincare solutions that combine efficacy with a high level of gentleness.
Molecular Structure of Lactoferrin (from the web, edited with AI tools)
100% Human-Derived Full-Length Structure
Prorylia™ LF features a 100% human-derived, full-length apo-lactoferrin structure, offering high biocompatibility and functional activity. This structural profile enables effective interaction with the skin environment and supports optimal utilization at the skin surface.
Scientific studies demonstrate that Prorylia™ LF exhibits antimicrobial and anti-inflammatory properties, including the inhibition of Cutibacterium acnes, supporting healthier skin in acne-prone individuals. Additionally, Prorylia™ LF may help reduce inflammation caused by external stressors, relieving discomfort from skin sensitivity—such as redness, burning, or stinging—and promoting a balanced skin microenvironment.
Multiple in vitro studies further indicate that Prorylia™ LF can strengthen the skin’s natural defenses, support structural integrity, and enhance moisture retention, contributing to a resilient and healthy skin barrier.
Core Mechanism of Lactoferrin (Cited from “Lactoferrin: A glycoprotein that plays an active role in human health” DOI: 10.3389/fnut.2022.1018336)
AI-Driven, End-to-End Biofoundry
The development and commercialization of Prorylia™ LF are enabled by Bota’s advanced biofoundry, which integrates AI-driven biological computation, high-throughput screening, experimental validation, and industrial-scale production. This end-to-end biofoundry accelerates the journey from laboratory to market while ensuring consistent, scalable results.
Looking forward, Yucca will continue to launch naturally derived, high-performance bio-based personal care ingredients, offering safer, more effective, and more sustainable solutions, and advancing innovation and transformation across the personal care industry.
About Yucca Elements
Yucca Elements is a wholly owned subsidiary of Bota Bio, a global biotechnology company. Relying on Bota Bio’s end-to-end biotechnology platform and the team members’ keen insight into market demand and consumer preferences, it is able to combine technology with market demand to provide consumers with better personal care ingredients. Yucca Elements uses the world’s leading biotechnology level to create natural, pure, and highly effective bio-based ingredients, and continues to promote global innovation in personal care ingredients and product ingredients.